Tag: LBCL

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Bispecific anti-CD20 and anti-CD19 CAR T Cell Therapy Shows Efficacy in B Cell M...

Nirav N. Shah, MD, an associate professor at the Medical College of Wisconsin, discusses bispecific anti-CD20 and anti-CD19 chimeric antigen receptor (CAR) T cells in a phase 1 dose escalation and expansion trial (NCT03019055) for relapsed B cell malignancies.

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Targeted5

Unanswered Questions Remain in DLBCL With Use of CAR T-Cell Therapies

In an interview with Targeted Oncology, Caron Jacobson, MD, discussed the data supporting use of CAR T-cell therapy as treatment of patients with diffuse large B-cell lymphoma and some of the remaining questions in this space that need to be addressed as these cellular therapies advanced forward in the field.

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targeted4

Off-the-Shelf CAR T-Cell Products Show Potential in DLBCL

  Nov 03 2020 Tagged CAR-T, LBCL, NHL

Loretta J. Nastoupil, MD, an assistant professor in the Department of Lymphoma/Myeloma at The University of Texas MD Anderson Cancer Center, discusses the use of off-the-shelf chimeric antigen receptor (CAR) T-cell products for the treatment of patients with diffuse large B-cell lymphoma (DLBCL) and other cancers.

https://www.targetedonc.com/view/off-the-shelf-car-t-cell-products-show-potential-in-dlbcl
blood a

Venous thromboembolism associated with CD19-directed CAR T-cell therapy in large...

Cancer-associated venous thromboembolism (VTE) constitutes a major cause of morbidity and mortality in patients with hematologic malignancies.1 VTE can occur after chimeric antigen receptor (CAR) T-cell therapy, whereas coagulopathy in the form of low fibrinogen and bleeding can be complications of cytokine release syndrome (CRS).

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blood cancer journal

Infection during the first year in patients treated with CD19 CAR T cells for di...

CD19-targeted chimeric antigen receptor (CAR) T cell therapy is an effective treatment for diffuse large B cell lymphoma (DLBCL).

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