Tag: CAR-T

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Immunotherapy Web Featured Images 109

Browse this week's featured selection of scientific publications

A new selection of scientific publications relating to the latest developments in immunotherapy are added to our website weekly. Here are are a few highlights from this week.

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CAR-T cells engineered to target a common genetic alteration: Loss of heterozyg...

  Mar 18 2021 Tagged CAR-T

Researchers developed a prototype for a new cancer immunotherapy that uses engineered T cells to target a genetic alteration common among all cancers.

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Onclive26

Frontline Axi-Cel Elicits 74% CR Rate in High-Risk Large B-Cell Lymphoma

Axicabtagene ciloleucel elicited a high objective response rate of 85%, with a complete response rate of 74% when used as a first-line therapy in patients with high-risk large B-cell lymphoma.

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onclive7

Risk-Adapted CAR T Dosing Maintains Efficacy, Improves Safety in Pediatric Relap...

A risk-adapted CD19 CAR T-cell therapy dosing approach allowed pediatric patients with relapsed/refractory acute lymphocytic leukemia to maintain a high rate of remission, while reducing the risk of severe toxicities among those with a high initial disease burden.

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Onclive28

Brexucabtagene Autoleucel Displays Continued Durability, Safety in Relapsed/Refr...

Brexucabtagene autoleucel displayed significant and durable responses and a reduction in adverse effects in patients with relapsed/refractory mantle cell lymphoma.

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Immunotherapy Web Featured Images 123

Experimental safety switch reduces severity of CAR-T immunotherapy-related side ...

UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur.

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Immunotherapy Web Featured Images 2

Immunotherapy Is on the Cusp of Major Breakthroughs in Multiple Myeloma

Just a decade ago, immune therapy for multiple myeloma barely existed as an idea. Since then, immune therapy has evolved rapidly and the field is on the verge of major improvements in outcomes.

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Immunotherapy Web Featured Images 109

Browse this week's featured selection of scientific publications

A new selection of scientific publications relating to the latest developments in immunotherapy are added to our website weekly. Here are are a few highlights from this week.

Visit website
Onclive17

Relapsed/Refractory DLBCL Undergoes Rapid Evolution With CAR T-Cell Therapy, ADC...

High-dose chemotherapy and transplant remains the second-line standard of care for the majority of patients with relapsed/refractory diffuse large B-cell lymphoma; however, CAR T-cell therapy and other novel agents, which have transformed the third-line setting, may offer alternative and more personalized second-line options in the coming years.

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Onclive19

Multi-Agent Therapy May Overcome CAR T Resistance in B-Cell Malignancies

Treatment with chimeric antigen receptor T-cells has induced unprecedented overall response rates and complete response rates in patients with relapsed/refractory B cell malignancies.

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